Course Syllabus

Fall 2015

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The course gives a comprehensive entry-level introduction to bioinformatics. The course will present bioinformatics in the context of health informatics. It covers a wide variety of topics in bioinformatics, including sequence analysis, protein structure, genome analysis, proteomics data analysis, database, transcription profiling, etc, and how they may be used in clinical practices. The potential future impact of bioinformatics in health information system will also be discussed. The goals of the course include 1) help students understand the scope, the basic concepts and the theory of bioinformatics and 2) gain experience with the use of tools for bioinformatics related data analysis. Programming skills are not necessary. Laptop computer is necessary if students want to practice bioinformatics software and tools in class. This course will be offered as an online course.

Course Instructor

W. Jim Zheng, Ph.D
Associate Professor
E-mail: Wenjin.J.Zheng@uth.tmc.edu
Phone: 713-500-3641 Fax: 713-500-3907

Welcome

Topic Schedule

Week Topic
1 Module 1: Class overview: Introduction to bioinformatics and history of bioinformatics
2 Module 2: What is bioinformatics? Role of bioinformatics in translational research and clinical practices
3 Module 3: Biological information-categories, acquiring biological information
4 Module 4: Biological information analysis - Sequence analysis
5 Module 5: Biological information analysis - Transcription profiling by different methods. Biomarker discovery
6 Module 6: Biological information analysis - Next generation sequence and its impact on clinical practice
7 Midterm
8 Module 7: Student presentation - Proposal of class projects
9 Module 8: Biological information analysis - Biological networks and human diseases
10 Module 9: Biological information analysis - Guest lecture
11 Module 10: Biological information analysis - Genetic variations and personalized medicine
12 Module 11: Biological information analysis - Microbiome and human health
13 Module 12: Biological information dissemination - Web resources and tools
14 Module 13: Biological information dissemination - Ethics, security and practice
15 Module 14: Student presentation - Project final submission
16 Final

Course Summary:

Date Details Due